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Indian scientists produce most detailed 3D atlas of the human brainstem

182 points by BaudouinVH - 20 comments
yalogin [3 hidden]5 mins ago
I am sure this is great but it requires some depth in that field to appreciate this. I don’t understand if what they developed is a tech to do a live scan of any person or just a detailed map of one brain.
rramadass [3 hidden]5 mins ago
You can see the 3d atlas videos at the project website online - https://anchor.humanbrain.in/
21asdffdsa12 [3 hidden]5 mins ago
+1 for indian public funded science being publicly available and feeling the need to justify their existence by explaining what they do to the public.
iandanforth [3 hidden]5 mins ago
The article sometimes makes it sound like this is a diagnostic tool but am I wrong in thinking it's a reference constructed from a small number of individuals?
deskamess [3 hidden]5 mins ago
Correct...

"Anchor is not a diagnostic tool. Instead, its greatest value lies in the questions it could help answer."

and

"Users can zoom from the whole brainstem seen on MRI down to individual neurons while maintaining their precise spatial relationships."

Thats pretty cool. The diagnosis/evaluation is still in the hands of another entity (doctor/scientist/AI assistant). More samples (via end of life donations) would help understanding, early diagnosis, and hopefully/eventually cures.

pchangr [3 hidden]5 mins ago
my understanding is that they took 3 specimens, aged 25 gestational weeks, 9 and 54 years old.. did “800 serial histological sections” and manually tagged them. But you can check out the information yourself here: https://anchor.humanbrain.in/
CubicalOrange [3 hidden]5 mins ago
> The researchers have made the atlas freely available online

fuck yes. finally someone not gatekeeping lifesaving technologies so they can make shit ton of money out of it.

pchangr [3 hidden]5 mins ago
I believe this is how most publicly funded research and some private research institutes work. This research was conducted by a public Indian university (IIT Madras). Which, by the way is literally more selective than IVY league universities
hsb3 [3 hidden]5 mins ago
Doesnt matter how selective they are if the Budget of 1 MIT is $5 Billion while the budget of all 23 IIT is less than $1 Billion. There is a reason why so many Indian scientists move out of India.
higginsniggins [3 hidden]5 mins ago
I'm not sure what point you're making, but if anything, that makes this MORE impressive not less, if they can do great work with little resources.
pchangr [3 hidden]5 mins ago
I think it’s good for people outside of India (myself included) to know how competitive life is over there. Indian research institutes seem to be truly top notch and they deserve due respect. That was my reason to share.
pchangr [3 hidden]5 mins ago
I just thought it was a cool fact :)
hgoel [3 hidden]5 mins ago
Selectivity is just a numbers game, doesn't translate well in the way you're trying to present.
porridgeraisin [3 hidden]5 mins ago
This particular lab happens to be primarily privately funded, donations, grants, etc,. Most big ticket research at IITM like this one are industry-funded or donation-funded. The public funds cover all the usual stuff and I don't mean to understate it.
pchangr [3 hidden]5 mins ago
Oh, I could find just the founding statement of the project stating it was funded by the “Principal Scientific Advisor” of the government of India https://acr.iitm.ac.in/iitm_in_news/iit-madras-launches-sudh... did you find something different?

Edit: it seems you were right. Apparently they have received big donations from ex-alumni including the co-founder of infosys and the founder of Fairfax Financial Holdings. Pretty cool!

rramadass [3 hidden]5 mins ago
The article you linked to itself states;

The centre will power a large-scale multi-disciplinary effort to map human brains at cellular level. It is supported by Infosys co-founder and IIT Madras’ Distinguished Alumnus Kris Gopalakrishnan and his wife Sudha Gopalakrishnan. Since 2014, Gopalakrishnan has been involved in seeding research at the institute at the intersection of neuroscience and engineering.

philipallstar [3 hidden]5 mins ago
Me hiring a PA is literally more selective than that. Only one person can qualify.
pchangr [3 hidden]5 mins ago
I should have clarified that I was defining selectivity as the ratio between applicants and accepted candidates. Getting in this school requires someone to be among the top 250k takers of a specific exam (JEE main) typically, it’d be taken by around 1.5 million students. If one is among those 250k, one can choose to do the advanced test.. which in 2025 was cleared by 56 880 students .. from which, 18,188 students were admitted.

And yes, if you have more than .. 84 candidates, your process would be more selective. However, I think the fair comparison would be .. say .. the MIT?

On the same year, the MIT got 29,282 applications and admitted 1,324 students

So if you apply to the MIT you’re more than 3 times likelier to get accepted.

epestr [3 hidden]5 mins ago
Not a fair comparison. IITs are a bottleneck given there aren't better (in terms of reputation and outcome) schools here. And plenty more apply simply because it's a rite of passage for every Indian kid. I'd guess less so for MIT given kids pre-reject themselves.

Speaking anecdotally, of course.

porridgeraisin [3 hidden]5 mins ago